Hive Publications

Novel reference genes in colorectal cancer identify a distinct subset of high stage tumors and their associated histologically normal colonic tissues. BMC Med Genet. 2019

Development of an integrated platform using multidisciplinary real-world data to facilitate biomarker discovery for medical products. Clin Transl Sci. 2019

Enabling Precision Medicine via standard communication of NGS provenance, analysis, and results, BioRxiv, 2018

Bio-compute objects – a step towards validation of bio-medical scientific computations. PDA J Pharm Sci Technol. 2017

High-performance Integrated Virtual Environment (HIVE): a robust infrastructure for Next-Generation Sequence Data Analysis. Database (Oxford). 2016

Challenges, solutions, and quality metrics of personal genome assembly in advancing precision medicine. Pharmaceutics. 2016

FDA’s Activities Supporting Regulatory Application of “Next Gen” Sequencing Technologies. PDA J Pharm Sci Technol. 2014

Advantages of distributed and parallel algorithms that leverage Cloud Computing platforms for large-scale genome assembly. Research 2015

High-Performance Integrated Virtual Environment (HIVE) Tools and Applications for Big Data Analysis. Genes 2014

Human germline and pan-cancer variomes and their distinct functional profiles. Nucleic Acids Research, 2014

A framework for organizing cancer related variations from existing databases, publications and NGS data using a High-performance Integrated Virtual Environment (HIVE). Database. 2014

Non-synonymous variations in cancer and their effects on the human proteome: workflow for NGS data biocuration and proteome-wide analysis of TCGA data. BMC Bioinformatics. 2014